1
Research Platform
Published Research: Annals of Vascular Surgery
14 ESVS Guidelines Unified
Research over published vascular surgery guidelines
ESVS Guideline Research Tool
ClinicalGuidelines.io is a retrieval-augmented clinical decision support tool over 14 ESVS guidelines.
For research and evaluation only. Not a medical device and not for clinical use. Do not enter real patient-identifiable information. Responses are generated from published ESVS guidelines and have not been validated for clinical accuracy.
14
Published ESVS guidelines form the system's retrieval scope.
Router
Routes requests among the included guidelines.
Context Gate
Requests missing detail in predefined scenarios; coverage is incomplete.
Sources
Retrieval uses narrative text and structured recommendations.
Query Handling
The system handles guideline questions and requests missing clinical detail in predefined scenarios. This check does not cover all presentations.
Knowledge Questions
Guideline questions proceed to retrieval from the included sources.
Specified Research Cases
Cases with the parameters requested by the system proceed to retrieval.
Missing Clinical Detail
The Context Gate requests missing clinical detail in predefined scenarios; it does not cover all presentations.
Questions Outside Scope
The system will decline questions outside the 14 ESVS guidelines.
Published Research
The chart below relates to the earlier single-guideline application published in Annals of Vascular Surgery.
The earlier study does not establish clinical accuracy for the 14-guideline system. Its answers have not been assessed for clinical acceptability by expert reviewers; that evaluation is planned.
14
ESVS Guidelines
The system's retrieval scopeDual
Retrieval Channels
Narrative text and structured recommendationsContext Gate
Clarification Prompts
Requests missing detail in predefined scenariosRetrieval Architecture
The pipeline incorporates query interpretation, guideline routing, clarification prompts, and retrieval from narrative text and structured recommendations.
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Pre-retrieval interpretation
The incoming query is classified as a guideline question or a case for which clinical detail may be requested.
02
Guideline Router Service
The router selects among the 14 included ESVS guidelines.
03
Context Gate
The system requests missing clinical detail before advising, but this check does not cover all presentations.
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Dual-channel retrieval
Retrieval uses both narrative guideline text and structured recommendations.
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Response generation
Responses are generated from published ESVS guidelines and have not been validated for clinical accuracy.
Known limitations.
The system is constrained to 14 ESVS guidelines and will decline questions outside them. It requests missing clinical detail before advising, but this check does not cover all presentations. Its answers have not been assessed for clinical acceptability by expert reviewers; that evaluation is planned. PHI de-identification has not been tested on real data.
Planned Evaluation
Assessment of the answers for clinical acceptability by expert reviewers is planned.
Research plans
Hellenic Society of Vascular and Endovascular Surgery
Prospective multicenter evaluation in conjunction with HSVES is planned.
The system's answers have not been assessed for clinical acceptability by expert reviewers.
Publications
Published studies from the research group in Annals of Vascular Surgery.
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An Artificial Intelligence Application for Standardized Expert-Level Interpretation of Vascular Clinical Practice Guidelines
Ann Vasc Surg. Published 2026 Jul;128:473-483. doi: 10.1016/j.avsg.2026.03.020. PMID: 41895597.
This publication concerns the earlier single-guideline application. It does not establish clinical accuracy for the 14-guideline system.
Presentations
Conference presentations from the research group. Titles are reproduced as presented and do not establish clinical accuracy or regulatory approval of the system.
48th CX Vascular and Endovascular Consensus Update
ExCeL London, United Kingdom
Thursday, 23 April 2026
- Time
- 17:05 - 17:10
- Location
- Theatre 3
- Talk
- Clinicalguideline IO: Transforming guidelines into intelligence
39th ESVS Annual Meeting
Istanbul, Türkiye
23-26 September 2025
- Session window
- Tuesday 23 September, 13:00 - 17:30
- Reference
- AS-ESVS-2025-00397
- Abstract
- An Artificial Intelligence companion app that provides expert-level interpretation of clinical practice guidelines
SITE Barcelona 2025
Barcelona, Spain
15-17 October 2025
Presentation of the ClinicalGuidelines.io concept.
25th Panhellenic Congress of Vascular & Endovascular Surgery - Angiology
Larissa Imperial, Larissa, Greece
19-21 March 2026
- Session
- Friday, 20 March 2026, 09:00 - 10:00
Session 3: Innovation, Technology, and Entrepreneurship in Vascular Surgery - Talk
- No Hallucinations, Just Guidelines: CE-Marking an AI Companion as a Medical Device
Scientific Leadership
A multidisciplinary leadership group spanning vascular surgery, academic medicine, and translational clinical AI.
Vangelis Alexiou, MD, PhD
Assistant Professor of Vascular Surgery
University of Patras, Greece
Areti Vassiliou, MD, MSc
Vascular Fellow
Attikon University Hospital, Athens
Prof. Bauer E. Sumpio, MD, PhD
Professor of Surgery
Yale University School of Medicine, USA
Prof. George Geroulakos, MD, PhD
Professor of Vascular Surgery
National and Kapodistrian University of Athens
Prof. Stavros K. Kakkos, MD, PhD
Professor of Vascular Surgery
University Hospital of Patras, Greece
Request Research Access
Request access for research and evaluation or register interest in the planned expert assessment.
For research and evaluation only. Not a medical device and not for clinical use. Do not enter real patient-identifiable information. Responses are generated from published ESVS guidelines and have not been validated for clinical accuracy.